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IGF-II R

概要

Name:Insulin-like growth factor II receptor
Target Synonym:Insulin-like growth factor 2 receptor,IGF-II receptor,CD222,Insulin Like Growth Factor 2 Receptor,M6P/IGF2R,M6P/IGF2 receptor,CI Man-6-P receptor,Insulin-like growth factor II receptor,IGF2R,300 KDa Mannose 6-Phosphate Receptor,MPR 300,MPRI,Cation-Independent Mannose-6-Phosphate Receptor,Cation-Independent Mannose-6 Phosphate Receptor,CD222 Antigen,CI-M6PR,MPR300,CI-MPR,CIMPR,M6P-R,MPR1,M6PR,Receptor, IGF Type 2
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Approved

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製造番号 種類 製品説明 構造 純度 特徴
IGR-H52H3 Human Human IGF-II R Protein, His Tag
IGR-H52H3-structure
IGR-H52H3-sds
ACRO Quality

生物活性データの一部

IGR-H52H3-BLI
 IGF-II R BLI

Loaded Human IGF-II R Protein, His Tag (Cat. No. IGR-H52H3) on HIS1K Biosensor, can bind Human IGF-II, Fc Tag (Cat. No. IG2-H4260) with an affinity constant of 15.6 nM as determined in BLI assay (ForteBio Octet Red96e) (QC tested).

IGR-H52H3-ELISA
 IGF-II R ELISA

Immobilized Human IGF-II, Fc Tag (Cat. No. IG2-H4260) at 5 μg/mL (100 μL/well) can bind Human IGF-II R Protein, His Tag (Cat. No. IGR-H52H3) with a linear range of 0.010-0.313 μg/mL (Routinely tested).

公開薬物情報

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Avalglucosidase alfa neoGAA; GZ-402666; Neo-rhGAA; NeoGAA Approved Genzyme Corp Nexviazyme, Nexviadyme, 耐而赞 United States Glycogen Storage Disease Type II Genzyme Corp 2021-08-06 Glycogen Storage Disease Type II Details

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